2017 marks the centenary of two of the most creative scientists of the 20th century, Prof David Bohm FRS (1917 – 1992) and Prof Vicomte Ilya Prigogine (1917 – 2004). Both men thought out-of-the-box, and introduced new and influential concepts that have had a wide reach outside their specialist fields. The Network arranged a weekend of dialogue with David Bohm in 1988, and a day with Ilya Prigogine in 1995, which was attended by more than 400 people. Both were Honorary Members. Addressed by experts who worked closely with both men, this centenary conference will consider their legacies and the extensive influence, showing how their ideas still shape our thinking.